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The structural analysis and the SOD‐like activity of CuII complexes [(Cu)(C16H18N3O5)]ClO4 (1) and [(Cu)4(C36H52N8O12)] (2) are described with ligands obtained from the condensation of picolinaldehyde and 2‐formylpyrrole with tris(hydroxymethyl)aminomethane (TRIS). Finally, complex 1 catalyzes the dismutation of superoxide efficiently with IC50 values in the range of 0.43 micromolar solution, evaluated through the inhibition of the photoreduction of nitro blue tetrazolium (NBT) (superoxide dismutase assay).
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Canabarro et al. (2016) studied this question.
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