Key result
Acute coronary occlusion and CHF are linked to higher plasma-hydrocortisone levels, peaking in fatal cases.
Why the study?
The plasma-hydrocortisone level in patients with acute coronary occlusion and congestive heart failure was examined to understand its variation and clinical significance.
Are plasma-hydrocortisone levels elevated in patients with acute coronary occlusion or congestive heart failure compared to controls?
Comparison
Patients with heart disease vs control patients
Design
Observational cohort study with repeated plasma-hydrocortisone measurements
Authors
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May indicate severity and mortality risk in acute coronary occlusion or heart failure; leaves open causal role and therapeutic implications.
Observational (n=34)
Are plasma-hydrocortisone levels elevated in patients with acute coronary occlusion or congestive heart failure compared to controls?
Plasma-hydrocortisone levels are significantly elevated in acute coronary occlusion and heart failure, and the highest levels are associated with mortality.
Hansen et al. (1969) conducted an observational in Heart disease (n=34). Acute coronary occlusion and congestive heart failure vs. Control patients was evaluated on Plasma-hydrocortisone level. Acute coronary occlusion and congestive heart failure were associated with significantly higher plasma-hydrocortisone levels compared to controls, with the highest values in patients who died.
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