Synthesis of novel fused heterocyclic system: 5-(substituted)-5-oxo-5H-6,12-dioxa-5λ5–phosphabenzo (a) anthracene-7-ones

Synthesis of new fused phosphorus heterocyclic derivatives, phosphabenzo[a]anthracene-7-ones, is accomplished by a new methodology involving Friedel-Crafts insertion of phosphorus trichloride into 3-flavanol in the presence of ZnCl 2 as a catalyst and subsequent reaction of the resultant chloroxaphosphorin with various alcohols in the presence of triethylamine, followed by oxidation with H 2 O 2 .The structures were determined by IR, 1 H, 13 C, 31 P NMR and mass spectral (MS) studies.They were screened for antifungal and antibacterial activity.