Key result
Radical and extended nephrectomy yields 16-month recurrence-free survival in a patient with renal leiomyosarcoma.
Why the study?
Renal leiomyosarcoma is a very rare malignant tumour with poor prognosis and limited clinical descriptions available.
Case Report (n=1)
No
Renal leiomyosarcoma is an exceptionally rare malignancy where differential diagnosis relies heavily on immunohistochemical findings.
Renal leiomyosarcoma case underscores diagnostic challenges and poor prognosis; leaves open optimal management strategies pending prospective data.
Renal sarcomas are very rare malignant tumours with a very poor prognosis. Renal leiomyosarcoma, a malignant tumour of smooth muscle origin, is the most common histological type. The article reports a case of leiomyosarcoma of renal location, with a review of the literature. A 38-year-old female patient, with no previous pathological history, consulted the nephrology department of the Teaching Hospital of Lomé for abdominal pain that had been present for 4 years. Histology showed a tumour proliferation of fasciculated architecture, made of spindle cells arranged in long bundles, with cytonuclear atypia and cytoarchitectural abnormalities. Immunohistochemical examination showed positive staining for smooth muscle actin, h-caldesmone, desmin and CD34 and negative for pancytokeratin (AE1/AE3), myogenin and PS100. Renal leiomyosarcoma is an exceptional malignancy. It remains the most common renal sarcoma, the differential diagnosis of which is based on immunohistochemical findings.
No takes yet. Share an insight, caveat, or question.
Djiwa et al. (2022) conducted a case report in Renal leiomyosarcoma (n=1). Radical and extended nephrectomy was evaluated on Recurrence-free survival. A 38-year-old woman with renal leiomyosarcoma underwent radical and extended nephrectomy and remained free of recurrence after a 16-month follow-up.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: