Key result
Type 1 diabetes linked to ~57% lower meal-induced proximal stomach volume response versus healthy controls.
Why the study?
Poor relaxation in the stomach after a meal may contribute to disturbed gastric emptying and abdominal discomfort in patients with diabetes mellitus, but the relationship with vagal neuropathy is unclear.
Do patients with type 1 diabetes mellitus have impaired meal-induced gastric volume responses compared to healthy controls?
Case-Control (n=32)
Do patients with type 1 diabetes mellitus have impaired meal-induced gastric volume responses compared to healthy controls?
Absolute Event Rate: 49.4% vs 114.9%
p-value: p=0.04
Patients with type 1 diabetes mellitus exhibit impaired meal-induced gastric volume responses, which correlates with reduced vagal tone.
No takes yet. Share an insight, caveat, or question.
Impaired proximal gastric response in T1DM is hypothesis-generating; leaves open its link to symptoms or vagal tone in prospective studies.
Undeland et al. (1997) conducted a case-control in Type 1 diabetes mellitus (n=32). Type 1 diabetes mellitus vs. Healthy controls was evaluated on Meal-induced volume response of the proximal stomach (area under time-volume curve 0-30 min) (p=0.04). Type 1 diabetes mellitus was associated with a significantly lower meal-induced volume response of the proximal stomach compared to healthy controls (49.4 vs 114.9 min.mL; P=0.04).
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