Key result
Diabetes, obesity, and autonomous neuropathy were associated with impaired gallbladder emptying, with larger residual volumes in patients with autonomous neuropathy versus controls (P<0.03).
Why the study?
Does diabetes, neuropathy, and obesity affect gallbladder volume and emptying?
Population
76 subjects: 21 diabetics and 55 healthy volunteers.
Comparison
Test meal vs Healthy volunteers
Design
Cross-sectional
Authors
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Fasting GB volume similar by diabetes/neuropathy status and tied to BMI; leaves open postprandial effects in larger studies.
Observational (n=76)
Does diabetes, neuropathy, and obesity affect gallbladder volume and emptying?
p-value: p=<0.03
Diabetes, particularly when complicated by autonomic neuropathy and obesity, is associated with impaired gallbladder motility and emptying.
Palasciano et al. (1992) conducted an observational in Diabetes (n=76). Diabetes vs. Healthy volunteers was evaluated on Post-prandial gallbladder emptying and residual volume (p=<0.03). Diabetes, obesity, and autonomous neuropathy were associated with impaired gallbladder emptying, with larger residual volumes in patients with autonomous neuropathy versus controls (P<0.03).
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