Key result
Trabeculated embryonic myocardium exhibits rapid stress relaxation and ~30% hysteresis versus younger compact myocardium.
Why the study?
The passive viscoelastic behavior of trabeculated embryonic myocardium and its difference from compact myocardium and quasi-linear models was not well characterized.
Population
Excised left ventricular sections from stage-21 and stage-24 trabeculated and stage-16 and stage-18 compact embryonic chick myocardium
Comparison
Trabeculated myocardium vs compact myocardium and quasi-linear viscoelastic model predictions
Design
Biomechanical testing including ramp-and-hold stress relaxation and sinusoidal stretching
Authors
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Animal data on embryonic myocardial viscoelasticity warrant caution in clinical translation; hypothesis-generating for developmental cardiac biomechanics.
The passive viscoelastic behavior of trabeculated embryonic myocardium differs markedly from younger compact myocardium and does not follow a quasi-linear model.
Miller et al. (2000) studied Embryonic cardiovascular function. Trabeculated embryonic myocardium (stage-21 and stage-24) vs. Compact myocardium (stage-16 and stage-18) was evaluated on Passive viscoelastic behavior (stress relaxation and hysteresis). Trabeculated embryonic myocardium exhibited rapid stress relaxation and non-quasi-linear viscoelastic behavior, with hysteresis ranging from 25-35%, compared to younger compact myocardium.
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