Answers are grounded in this paper and cite their sources.
The Human Transition Protein 1 gene (TNPl) probe (1) used was a 700 bp genomic DNA sequence cloned into the SmaI site of pUC8 and was supplied by W.Engel. Polymorphisms: TNPl identifies a two allele polymorphism with TaqI: Al = 9.6 kb; A2 = 8.4 kb.Frequency: Analysis of 20 unrelated individuals yielded frequencies: Al = 0.23; A2 = 0.77.Not Polymorphic For: Banl, BclI, BglI, BstEII, EcoRI, HaeIII, HindIII, MspI, NcoI, PstI, PvuII, RsaI in a screen of 10-20 unrelated individuals.Mendelian Inheritance: Autosomal co-dominant segregation has been demonstrated in 3 families.
No takes yet. Share an insight, caveat, or question.
Hoth et al. (1991) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: