Key result
Nine combined revascularization and valve interventions exist for ischemic mitral regurgitation but lack detailed study.
Why the study?
Ischemic mitral regurgitation involves complex coronary artery disease and mitral regurgitation with multiple treatment options that have not been studied in detail.
Highlights the need for comparative analysis of nine potential combinations of coronary revascularization and mitral valve interventions for ischemic mitral regurgitation to guide patient-specific treatment.
Multiple unstudied options exist for ischemic mitral regurgitation; comparative trials needed before guiding patient-specific therapy.
Ischemic mitral regurgitation (IMR) is a complicated medical condition with varying degrees of coronary artery disease and mitral regurgitation (MR). The traditional surgical treatment option for those with indications for intervention is coronary artery bypass grafting (CABG) plus or minus mitral valve repair or replacement (MVR). Percutaneous coronary intervention, hybrid coronary revascularization (HCR), and conventional CABG are three techniques available to address coronary artery disease (CAD). Percutaneous edge-to-edge repair, minimally invasive, and traditional sternotomy are accepted approaches for the treatment of MR. When taken in combination, there are nine methods available to revascularize the myocardium and restore competency to the mitral valve. While most of these treatment options have not been studied in detail, they may offer novel solutions to a widely variable and complex IMR patient population. Thus, a comparative analysis including an examination of potential benefits and risks will be helpful and potentially allow for more patient-specific treatment strategies.
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Scoville et al. (2015) conducted a review in Ischemic mitral regurgitation (IMR). Revascularization and mitral valve repair/replacement methods was evaluated. Nine methods are available to revascularize the myocardium and restore mitral valve competency in ischemic mitral regurgitation, though most have not been studied in detail.
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