Disagreement between splenic switch-off and myocardial T1-mapping after caffeine intake

Figures

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  Fig. 1. Illustrative presentation of T1-mapping results and SSO assessment based on a case of a 75-year old female that underwent multiple adenosine perfusion CMR evaluations within a short period of time due to: a technical failure during the first examination with leakage of adenosine through the extension set of the intravenous line causing inadequate adenosine induced hyperemia, b a second examination (14 days later) in which ingestion of coffee < 4 h examination was retrospectively determined and c a third final examination 7 days after the second examination without protocol conflicts. For illustrative purposes we present (from left to right) myocardial and splenic native T1-mapping analysis with endo- and epicardial contours graphically visualized (green lines) and regions of interest placed in the inferior septal region of the myocardium (pink) and in the spleen (yellow) with the use of dedicated software, a graphical illustration of the ΔT1 color maps and adenosine perfusion images. a Inadequate myocardial stress as shown by a very low ΔT1 of the myocardium (+ 0.2%, purple), minor stress changes of the spleen (purple) and no SSO. b Inadequate myocardial stress due to coffee…

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  Fig. 2. Boxplot of myocardial and splenic T1-reactivity (ΔT1) in patients with coffee intake < 4 h prior to the examination and patients with normal perfusion CMR and no recent coffee intake. There was a significant difference between myocardial and splenic ΔT1 in patients with normal perfusion CMR. No statistical difference was present in patients with coffee intake < 4 h prior to the examination

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  Fig. 3. Kaplan–Meier survival curve comparing patients with recent coffee intake to patients in the control group. MACE was defined as myocardial ischemia, myocardial infarction, heart failure or cardiac death. Log-rank test p-value < 0.001