Key result
Carotid plaque is linked to ischemic stroke, showing a ~170% higher prevalence versus controls.
Why the study?
Estimating carotid intima-media thickness and plaque is important for evaluating patients at higher risk of cardiovascular and cerebrovascular disease, but their predictive value for ischemic stroke needed investigation.
Does increased carotid intima-media thickness and plaque measured by ultrasound predict the occurrence of ischemic stroke?
Case-Control (n=52)
No
Does increased carotid intima-media thickness and plaque measured by ultrasound predict the occurrence of ischemic stroke?
Increased maximum intima-media thickness of the common and internal carotid arteries, along with plaque presence, are strong predictors of ischemic stroke.
Association between carotid plaque and ischemic stroke is hypothesis-generating; leaves open prospective validation for risk prediction.
B-mode ultrasound is a non-invasive method of examining the wall of the peripheral arteries And provides measures of the intimamedia thickness (IMT) at various sites (common carotid artery, internal carotid artery), and plaques that may indicate early pre symptomatic diseases; therefore, estimating the intima-media thickness and plaque is important in term of evaluating patients with higher risk of cardiovascular and cerebrovascular disease.Objectives: We investigated whether carotid intima-media thickness and plaque measured by noninvasive B-mode Ultrasonography predicts ischemic stroke.Methods and Patients: This is a case -control study of patients admitted to hospital with diagnosis of ischemic CVA ; and patients without ischemic infarction; the diagnosis of cerebral infarction was confirmed by new CT of the brain.All participants underwent the standard examination and testing as well as carotid B-Mode ultrasound (Ultrasound measurements of right and left common carotid artery IMT and internal carotid artery IMT were made) and arteries were examined for plaques 1.5 cm a above and below the flow divider.Result: 52 patients were included in the study, 26 patients with ischemic stroke(case subjects) and 26 patients (control subjects).Mean maximum common carotid artery IMT , internal carotid artery IMT and the prevalence of plaque were significant higher in CVA group ( P < 0.05 , p= 0,001 , p <0.001 , respectively), other risk factors showed no significant difference between groups.Conclusion: The present study demonstrated increased maximum IMT of the common carotid artery, internal carotid artery.And Plaque in ICA are strong predictors for ischemic stroke.
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Dr Asgad A. Abdalgbar (2016) conducted a case-control in Ischemic stroke (n=52). Carotid intima-media thickness and plaque vs. Controls without ischemic infarction was evaluated on Prevalence of carotid plaque (p=<0.001). The prevalence of carotid plaque was significantly higher in patients with ischemic stroke compared to controls (73% vs 27%, p<0.001).
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