Why the study?
Does the measurement of carotid intima media thickness and plaques improve the prediction of ischemic cerebrovascular events beyond the Framingham Stroke Risk Score in a general population?
Population
1348 subjects randomly taken from the census list of San Daniele Township
Comparison
Measurement of common carotid intima media… vs Framingham Stroke Risk Score alone
Design
Cohort
Follow-up
mean 12.7 years
Authors
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Supports selective carotid imaging for risk refinement only in high Framingham-score patients; leaves open utility and outcome impact in lower-risk groups.
Does the measurement of carotid intima media thickness and plaques improve the prediction of ischemic cerebrovascular events beyond the Framingham Stroke Risk Score in a general population?
Carotid intima media thickness and plaques are independent risk factors for vascular events, but their addition to the Framingham Stroke Risk Score only improves individual risk prediction in high-risk subjects.
Prati et al. (2008) studied this question.
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