Key result
This editorial concludes that lowering blood pressure to 130-139/80-85 mmHg appears safe, but the J-curve hypothesis and optimal targets urgently require correctly designed randomized trials.
Why the study?
Does intensive blood pressure lowering below 130 mmHg reduce cardiovascular events in hypertensive patients without causing a J-curve effect of increased risk?
Does intensive blood pressure lowering below 130 mmHg reduce cardiovascular events in hypertensive patients without causing a J-curve effect of increased risk?
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This editorial highlights that lowering systolic blood pressure below 130 mmHg in high-risk or diabetic patients does not provide additional cardiovascular benefit and may be associated with a J-curve of increased risk, supporting a target of 130-139/80-85 mmHg.
Alberto Zanchetti (2010) conducted an editorial in Hypertension. Antihypertensive treatment was evaluated. This editorial concludes that lowering blood pressure to 130-139/80-85 mmHg appears safe, but the J-curve hypothesis and optimal targets urgently require correctly designed randomized trials.
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