Key result
Chemical shift MRI yields 100% specificity for characterizing hyperattenuating adrenal adenomas.
Why the study?
The role of chemical shift MR imaging for characterizing hyperattenuating adrenal masses remains to be clarified.
Does chemical shift MR imaging accurately characterize hyperattenuating (>10 HU) adrenal masses as adenomas?
Population
36 patients with 38 hyperattenuating (>10 HU) adrenal masses
Comparison
Chemical shift MR imaging evaluating signal intensity decrease between in-phase and opposed-phase images
Design
Observational cohort study
Follow-up
At least 24 weeks for imaging stability or pathologic diagnosis
Authors
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May support chemical shift MR as a specific second-line test for hyperattenuating adrenal masses; leaves open need for prospective validation.
Observational (n=36)
Does chemical shift MR imaging accurately characterize hyperattenuating (>10 HU) adrenal masses as adenomas?
Chemical shift MR imaging is a highly specific and reasonably sensitive second-line test for characterizing hyperattenuating adrenal masses, particularly those with attenuation between 10 and 30 HU.
Haider et al. (2004) conducted an observational in Hyperattenuating adrenal masses (n=36). Chemical shift MR imaging vs. Reference standard (pathologic diagnosis or imaging stability) was evaluated on Sensitivity for hyperattenuating adenoma using a 20% signal intensity decrease threshold. Chemical shift MR imaging demonstrated 67% sensitivity and 100% specificity for characterizing hyperattenuating adrenal adenomas using a 20% signal intensity decrease threshold.
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