What question did this study set out to answer?

To evaluate probiotic strains of Bifidobacteria and Lactobacillus as alternative therapies against Salmonella typhimurium and clarify their protective mechanisms in broiler chickens.

June 12, 2020AnimalsOpen Access

Evaluation of Bifidobacteria and Lactobacillus Probiotics as Alternative Therapy for Salmonella typhimurium Infection in Broiler Chickens

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To evaluate probiotic strains of Bifidobacteria and Lactobacillus as alternative therapies against Salmonella typhimurium and clarify their protective mechanisms in broiler chickens.
Orally inoculated one-day-old Cobb broiler chicks with distinct probiotic strains for three days prior to S. typhimurium challenge.
Assayed in vitro adherence capabilities of probiotic strains using human intestinal epithelial Caco-2 cell models.
Monitored S. typhimurium recovery from cecal tonsils, host cytokine levels (IFN-γ and TNF-α), body weight gain, and food conversion ratios.
L. casei ATTC334 and B. breve JCM1192 strongly adhered to Caco-2 cells and reduced S. typhimurium recovery from cecal tonsils via competitive exclusion.
B. infantis BL2416 bound poorly to epithelial cells but stimulated IFN-γ and TNF-α production, effectively reducing pathogen recovery and improving weight gain alongside L. casei and B. breve.
B. longum Ncc2785 failed to adhere to epithelial cells or induce cytokine release, failing to prevent S. typhimurium colonization.

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Implication

Experimental study reveals specific Bifidobacteria and Lactobacillus strains inhibit Salmonella typhimurium colonization in broiler chickens, suggesting an effective alternative to antibiotics.

Cite This Study

El-Sharkawy et al. (2020) studied this question.

synapsesocial.com/papers/6aacf4611f76b1fd63e0fa12 https://doi.org/10.3390/ani10061023

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Implication

Experimental study reveals specific Bifidobacteria and Lactobacillus strains inhibit Salmonella typhimurium colonization in broiler chickens, suggesting an effective alternative to antibiotics.

Evaluation of Bifidobacteria and Lactobacillus Probiotics as Alternative Therapy for Salmonella typhimurium Infection in Broiler Chickens

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Discussion

Implication

Cite This Study

Evaluation of Bifidobacteria and Lactobacillus Probiotics as Alternative Therapy for Salmonella typhimurium Infection in Broiler Chickens

Key Points

Discussion

Implication

Cite This Study

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