Key result
Non-operated ICA maintains ~86% long-term freedom from stroke after contralateral endarterectomy.
Why the study?
The long-term risk and progression of disease in the non-operated internal carotid artery after contralateral carotid endarterectomy were not well characterized.
What is the long-term risk of stroke in the non-operated internal carotid artery territory after contralateral carotid endarterectomy?
Cohort (n=219)
What is the long-term risk of stroke in the non-operated internal carotid artery territory after contralateral carotid endarterectomy?
The long-term risk of stroke in the non-operated internal carotid artery territory is very small (1% per year), suggesting routine postoperative imaging surveillance may not prevent strokes.
Low stroke risk in non-operated ICA after contralateral CEA; hypothesis-generating for reduced surveillance needs in prospective cohorts.
The long-term fate of the non-operated internal carotid artery (ICA) in 219 patients undergoing contralateral carotid endarterectomy was studied; 151 patients underwent serial postoperative imaging of the vessel. Cumulative freedom from stroke in the non-operated hemisphere was 99, 96 and 86 per cent at 1, 5 and 10 years respectively, giving a mean incidence of stroke of 1 per cent per annum. Only one stroke was preceded by a transient ischaemic attack and no stroke was associated with severe (70 per cent or greater) stenosis of the ICA. Ten patients (7 per cent) with initially mild or moderate disease of the non-operated ICA progressed to severe stenosis during follow-up, but only three became symptomatic and, in each case, the onset of symptoms preceded recognition of disease progression. The long-term risk of stroke in the non-operated ICA territory is very small. Of practical importance is that none of the observed strokes could have been prevented by postoperative surveillance of this type.
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Naylor et al. (1995) conducted a cohort in Carotid artery disease (n=219). Non-operated internal carotid artery was evaluated on Cumulative freedom from stroke in the non-operated hemisphere at 10 years. The non-operated internal carotid artery after contralateral endarterectomy had a very small long-term stroke risk, with cumulative freedom from stroke of 86% at 10 years.
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