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It is shown that the canonical problem of classical statistical thermodynamics, the computation of the partition function, is in the case of ± J Ising spin glasses a particular instance of certain simple sums known as quadratically signed weight enumerators (QWGTs). On the other hand, it is known that quantum computing is polynomially equivalent to classical probabilistic computing with an oracle for estimating certain QWGTs. This suggests a connection between the partition function estimation problem for spin glasses and quantum computation. This connection extends to knots and graph theory via the equivalence of the Kauffman bracket polynomial and the partition function for the Potts model.
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