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January 22, 2024Advances in VirologyOpen Access

Respiratory viruses occur in ~53% of children hospitalized with acute respiratory infections, primarily influenza A.

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Why the study?

Acute respiratory tract infection is a major cause of morbidity and mortality in children, with various viruses contributing to disease but their prevalence in hospitalized children was not fully characterized.

Population

340 children hospitalized with acute respiratory tract infection at a teaching hospital in Shiraz, Iran

Design

Cross-sectional molecular diagnostic study using PCR

Key result

Respiratory viruses were detected in 52.64% of children hospitalized with acute respiratory tract infection, with influenza A (28.23%) and adenovirus (24.70%) being the most prevalent.

Authors

RFRana FarziNPNeda PirbonyehMKMohammad Rahim Kadivar

Discussion

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Overview

Viral pathogens detected in over half of pediatric ARTI hospitalizations; leaves open regional surveillance needs before guiding prevention.

Study Design

Type

Cross-Sectional (n=340)

Multicenter

No

Structured PICO

P
Population
340 children (mean age 3.13 years, 38.8% female) hospitalized with acute respiratory tract infection evaluated for the prevalence of respiratory viruses.
O
Outcome
Prevalence of influenza viruses A and B, adenovirus, respiratory syncytial virus (RSV), and human metapneumovirus (HMPV)

Over half of children hospitalized with acute respiratory tract infections had detectable viral pathogens, predominantly influenza A and adenovirus, highlighting the significant role of viral infections in this population.

Limitations

  • Lack of a control group to confirm the role of viral infection in disease pathogenesis (case-control studies recommended)

Cite This Study

Farzi et al. (2024) conducted a cross-sectional in Acute respiratory tract infection (ARTI) (n=340). Respiratory viruses (Influenza A and B, Adenovirus, RSV, HMPV) was evaluated on Prevalence of respiratory viruses. Respiratory viruses were detected in 52.64% of children hospitalized with acute respiratory tract infection, with influenza A (28.23%) and adenovirus (24.70%) being the most prevalent.

synapsesocial.com/papers/6aacfeb8299c72e8409c97fdhttps://doi.org/10.1155/2024/7613948
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Viral etiology of acute respiratory infections in children in Southern Iran2019 · 22 citations
  2. 2Viral Infections in Egyptian Hospitalized Children with Acute Respiratory Tract Infections2017 · 6 citations
  3. 3Etiology and Clinical Manifestations of Acute Respiratory Infections in Pediatric Patients: A Retrospective Study in Moscow, Russia2026
  4. 4Respiratory Viral Infections among Pediatric Inpatients and Outpatients in Taiwan from 1997 to 19992001 · 152 citations
  5. 5Viruses as Sole Causative Agents of Severe Acute Respiratory Tract Infections in Children2016 · 37 citations