Key result
TAVR alters mitral valve function by affecting LVOT obstruction and annular shape.
Why the study?
The impact of TAVR on mitral valve function, including mitral annular geometry and flow, is important to understand as TAVR use increases in patients with severe aortic stenosis and concomitant mitral regurgitation.
Does transcatheter aortic valve replacement affect mitral valve function and annular geometry in patients with severe aortic stenosis?
Does transcatheter aortic valve replacement affect mitral valve function and annular geometry in patients with severe aortic stenosis?
Understanding the impact of TAVR on mitral valve function and annular geometry is important for determining the feasibility of subsequent surgical or percutaneous mitral valve interventions.
TAVR may alter concomitant mitral regurgitation; leaves open whether pre- or post-TAVR mitral intervention improves outcomes.
The transcatheter aortic valve replacement (TAVR) procedure provides a way to treat severe aortic stenosis in the large population of patients who are not candidates for surgical aortic valve replacement. Mitral regurgitation is often concomitant to aortic stenosis in these patients due to the high pressure of the left ventricle and long-term damage to the mitral valve. Due to the proximity of the aortic valve to the mitral valve, TAVR can impact the functional status of the mitral valve by affecting left ventricular outlet obstruction and the mitral valve annular shape. As TAVR becomes increasingly prevalent to treat aortic stenosis, consideration into the impact of TAVR on mitral valve function is important in order determine whether patients will be able to undergo mitral valve repair or replacement, whether surgically or percutaneously. In this review, we seek to explore the effect of TAVR on the mitral annular geometry, mitral valve flow, and the impact of TAVR on the mitral valve in the presence of mitral annular calcification.
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Biswas et al. (2020) conducted a review in Severe aortic stenosis. Transcatheter aortic valve replacement (TAVR) was evaluated on Mitral annular geometry, mitral valve flow, and mitral valve function in the presence of mitral annular calcification. Transcatheter aortic valve replacement can impact the functional status of the mitral valve by affecting left ventricular outlet obstruction and the mitral valve annular shape.
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