Key result
HIIT with blood flow restriction improves BMI, body fat, and muscle mass vs moderate-intensity continuous training.
Why the study?
Does 12 weeks of aerobic exercise with blood flow restriction improve anthropometric indices in women with chemotherapy-induced cardiotoxicity?
RCT (n=20)
Single-blind
1:1:1:1
No
Does 12 weeks of aerobic exercise with blood flow restriction improve anthropometric indices in women with chemotherapy-induced cardiotoxicity?
p-value: p=<0.05
High-intensity interval training combined with blood flow restriction significantly improves anthropometric indices in women with chemotherapy-induced cardiotoxicity.
Supports HIIT with blood flow restriction for body composition in chemotherapy-induced cardiotoxicity; extends exercise options in cardio-oncology.
Introduction: Cardiotoxicity is an unavoidable complication after chemotherapy.The present study investigated the effect of 12 weeks of aerobic exercise (high-intensity interval training or moderate-intensity continuous training) with and without blood flow restriction on some anthropometric indices in women with breast cancer who had chemotherapy-induced cardiotoxicity.Methods: Twenty breast cancer patients with cardiotoxicity participated in this study (age: 21-34 years and body mass index: 26-57 kg/m 2 ).Patients were randomly divided into groups of high-intensity interval training, moderate-intensity continuous aerobic exercise, high-intensity interval training with limited blood flow, and moderate-intensity aerobic training with limited blood flow.Patients then received the interventions for 12 weeks, three sessions per week.Before and after the intervention, data related to patients' anthropometric indices were collected using a body composition analyzer (X-CONTACT 356) and analyzed using a MANCOVA test.Results: Weight, body mass index and final score of the body analyzer in the high-intensity interval training group with restricted blood flow improved significantly compared with the groups without restricting blood flow (P < 0.05).High-intensity interval training and restriction of blood flow reduced the percentage of body fat and age-appropriate body, increased muscle tissue, and the waist to hip ratio compared with moderateintensity continuous training (P < 0.05).Basal metabolic rate was not affected by exercise type but increased with blood flow restriction (P < 0.05). Conclusion:The present study suggests the use of a combination of physical activity and restriction of blood flow as a solution for the recovery of breast cancer patients with treatment-related cardiotoxicity (in the case of the components of the present study).
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Adimi et al. (2022) conducted an RCT in Cardiotoxicity after breast cancer treatment (n=20). High-intensity interval training with blood flow restriction (HIIT+BFR) vs. Moderate-intensity continuous training (MIT), HIIT without BFR, and MIT with BFR was evaluated on Anthropometric indices (body mass index, waist to hip ratio, percent body fat, and skeletal muscle mass) (p=<0.05). High-intensity interval training combined with blood flow restriction significantly improved body mass index, percent body fat, and skeletal muscle mass compared to moderate-intensity continuous training (P<0.05).
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