Key result
Polycystic ovary syndrome linked to differences in BMI, WHR, and insulin levels versus healthy women.
Why the study?
Polycystic ovary syndrome contributes to metabolic problems related to insulin resistance and hyperandrogenism and is closely related to body mass index, but the impact of age and BMI on hormonal disruption in PCOS is unclear.
Population
180 PCOS women and 170 age-matched healthy women from Mangalore, Karnataka
Comparison
PCOS women vs age-matched healthy women
Design
Case-control study
Authors
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Metabolic evaluation may merit consideration across PCOS BMI strata; leaves open independent effects of sex hormones on body composition.
Case-Control (n=350)
p-value: p=<0.01
PCOS women present with hyperandrogenism, insulin resistance, and low HDL-C levels, but changes in sex hormone levels had no significant impact on age or BMI in this South Indian cohort.
Hegde et al. (2022) conducted a case-control in Polycystic ovary syndrome (n=350). Polycystic ovary syndrome vs. Healthy women was evaluated on BMI and WHR (p=<0.01). Polycystic ovary syndrome was associated with significant differences in BMI and WHR (p<0.01), as well as plasma insulin and HOMA-IR (p<0.05), compared to healthy age-matched women.
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