Population
86 women of reproductive age with polycystic ovary syndrome, divided into four phenotypes.
Design
Cross-sectional
Key result
Women with hyperandrogenic polycystic ovary syndrome phenotypes A and B had significantly decreased HDL levels and increased triglycerides and LDL compared to those with the non-androgenic phenotype D.
Authors
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Supports exploring phenotype-specific CV risk in PCOS; leaves open prospective validation before changing practice.
Cross-Sectional (n=86)
No
Absolute Event Rate: 0.8% vs 1.6%
p-value: p=<0.05
Women with hyperandrogenic PCOS phenotypes exhibit more pronounced atherogenic dyslipidemia and impaired carbohydrate metabolism compared to those with non-androgenic phenotypes, highlighting a higher cardiovascular risk profile.
Abashova et al. (2021) conducted a cross-sectional in Polycystic ovary syndrome (n=86). Androgenic PCOS phenotypes (A and B) vs. Non-androgenic PCOS phenotype (D) was evaluated on HDL cholesterol level (mmol/L) (p=<0.05). Women with hyperandrogenic polycystic ovary syndrome phenotypes A and B had significantly decreased HDL levels and increased triglycerides and LDL compared to those with the non-androgenic phenotype D.
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