Key result
Normal contractile function fails to rule out chronic MI until transmural infarct extent reaches ~50%.
Why the study?
What is the relationship between contractile function and the transmural extent of infarction in patients with chronic reperfused myocardial infarction?
Population
31 patients with chronic coronary artery disease and single-vessel disease, evaluated 162 +/- 62 days after…
Design
Cross-sectional, Blinded observers for detecting abnormal thickening
Follow-up
162 +/- 62 days after reperfused first MI
Authors
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In chronic reperfused myocardial infarction, contractile dysfunction is often absent until the transmural extent of infarction approaches 50%, meaning normal function cannot rule out chronic MI.
Observational (n=31)
Single-blind
What is the relationship between contractile function and the transmural extent of infarction in patients with chronic reperfused myocardial infarction?
In chronic reperfused myocardial infarction, contractile dysfunction is often absent until the transmural extent of infarction approaches 50%, meaning normal function cannot rule out chronic MI.
Mahrholdt et al. (2003) conducted an observational in Chronic coronary artery disease (n=31). Transmural extent of infarction (TEI) was evaluated on Abnormal contractile function (wall thickening). The transmural extent of infarction approached 50% before contractile dysfunction could be systematically identified, indicating that normal contractile function cannot rule out chronic MI.
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