Key result
Rising NT-proBNP precedes sudden cardiac arrest in a neonate with isolated LVNC.
Why the study?
Assessment of NT pro-BNP levels combined with echocardiographic cardiac functional analysis may help predict disease progression in isolated left ventricular noncompaction (IVNC).
Case Report (n=1)
Assessment of NT-proBNP alongside echocardiography may help predict disease progression in neonates with isolated left ventricular noncompaction.
We describe here our expe rience with a neonate pre senting with cyanosis, grunting, and cardiome galy, who was diagnosed with isolate d le ft ventricular noncompaction (IVNC) by e chocardiography. The patient had high le vels of N-te rminal pro-B-type natriure tic pe ptide (NT pro-BNP) and symptoms of he art failure including poor fe eding and tachypnea. During the period in which NT pro-BNP levels ste adily incre ase d, the patie nt suffered sudde n cardiac arre st despite heart failure manageme nt. Following cardiopulmonary resuscitation, cardiac arrest was re solve d, NT pro-BNP le ve ls de crease d, and all symptoms showed improveme nt. We consider that asse ssment of NT pro-BNP with cardiac functional analysis using echocardiography could he lp in the prediction of disease progre ss in IVNC.
No takes yet. Share an insight, caveat, or question.
Song et al. (2009) conducted a case report in Isolated left ventricular noncompaction (IVNC) (n=1). N-terminal pro-B-type natriuretic peptide (NT pro-BNP) assessment was evaluated on Disease progression and cardiac arrest. In a neonate with isolated left ventricular noncompaction, increasing NT pro-BNP levels preceded sudden cardiac arrest, suggesting its utility in predicting disease progression.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: