Key result
Serial measurement of NT-proBNP levels was related to the velocity time integral over the aortic valve and indicated worsening haemodynamic status and death in a young woman with ccTGA.
Why the study?
Does serial measurement of NT-proBNP predict haemodynamic worsening and death in a patient with ccTGA?
Case Report (n=1)
Does serial measurement of NT-proBNP predict haemodynamic worsening and death in a patient with ccTGA?
Serial NT-proBNP measurement may help monitor haemodynamic status and predict outcomes in patients with ccTGA and a systemic right ventricle.
Serial NT-proBNP may track haemodynamics in ccTGA; hypothesis-generating and should not yet change practice.
The usefulness of natriuretic peptides to assess myocardial function in patients with a systemic morphological right ventricle is still unclear. In this report we describe the clinical course of a young woman with congenitally corrected transposition of the great arteries (ccTGA) who suffered from a progressive deterioration of myocardial function after child birth despite intensive medical treatment and additional cardiac resynchronization therapy. In this woman, serial measurement of NT-proBNP levels was related to the velocity time integral over the aortic valve and indicated worsening of the patient's haemodynamic status and finally death.
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Raedle-Hurst et al. (2010) conducted a case report in Congenitally corrected transposition of the great arteries (ccTGA) (n=1). Serial measurement of NT-proBNP levels was evaluated on Worsening of haemodynamic status and death. Serial measurement of NT-proBNP levels was related to the velocity time integral over the aortic valve and indicated worsening haemodynamic status and death in a young woman with ccTGA.
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