Key result
Genetic analysis of a rare Vietnamese rotavirus reveals bovine-human reassortment likely linked to Australian immune escape.
Why the study?
A rare human G10P[8] rotavirus with reassortment between bovine and human viruses was detected, and its evolutionary origin and genomic characteristics were unclear.
Population
A patient with acute gastroenteritis in Vietnam
Comparison
Genetic analysis of bovine-related VP7 region versus human rotavirus genes
Design
Case report with complete coding sequence genetic analysis
Authors
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May signal emerging rotavirus immune escape; leaves open need for expanded genomic surveillance before practice implications.
Case Report (n=1)
Identification of a rare human G10P[8] rotavirus reassortant in Vietnam suggests potential immune escape and cross-border transmission from Australia.
Matsushima et al. (2012) conducted a case report in Acute gastroenteritis (n=1). Genetic analysis of G10P[8] rotavirus was evaluated on Genomic constellation and genetic relationship. Genetic analysis of a rare human G10P[8] rotavirus from a patient in Vietnam revealed a reassortment between bovine and human viruses, likely originating from immune escape in Australia.
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