Key result
Surgical resection and subsequent chemotherapy shrink recurrent cardiac osteosarcoma metastasis within ~2 months.
Why the study?
Metastatic tumors of the heart are uncommon and treatment depends on metastasis location and primary tumor characteristics, with limited data on cardiac osteosarcoma.
Case Report (n=1)
This case report highlights the rare occurrence of metastatic cardiac osteosarcoma and demonstrates that a combined surgical and chemotherapeutic approach can be effective in managing recurrence.
Adds limited evidence for combined management of recurrent cardiac osteosarcoma; leaves open optimal strategies pending prospective data.
A 17-year-old female patient with a history of surgery for primary femoral and metastatic lung osteosarcoma was admitted to our clinic with palpitations. Upon evaluation, a metastatic osteosarcoma in the left ventricle was diagnosed. Based on the collaborative decision of the oncology and cardiovascular surgery clinics, surgery was performed and the patient was discharged without any problems. According to the recommendation of the oncology clinic, chemotherapy was postponed for 6 months after surgery. Five months postoperatively, however, she had a recurrence with 2 tumors. Based on the collaborative decision, chemotherapy was initiated and in 2 months the size of the recurrent tumors had diminished. The patient is still under the care of the oncology and cardiovascular surgery clinics and continuing her chemotherapy regimen. Osteosarcomas have a high mortality. Metastatic tumors of the heart are not common. The location of the metastasis and the characteristics of the primary tumor determine the treatment modality. In some previously published reports, various treatment choices have been described. In the present case report, we present a rare case with metastatic cardiac osteosarcoma.
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İyigün et al. (2010) conducted a case report in Recurrent cardiac metastasis of primary femoral osteosarcoma (n=1). Surgery followed by chemotherapy was evaluated on Clinical course (tumor recurrence and response to chemotherapy). In a 17-year-old female with cardiac metastasis of femoral osteosarcoma, surgical resection followed by chemotherapy after a 5-month recurrence led to diminished tumor size within 2 months.
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