Key result
Rare left ventricular osteosarcoma metastasis proves fatal at 30 months despite chemotherapy in adolescent male.
Why the study?
Cardiac metastasis of osteosarcoma is extremely rare and its clinical characteristics are not well described.
Case Report (n=1)
Cardiac metastasis of osteosarcoma is extremely rare and serves as a strong predictor of poor prognosis.
Left ventricular metastasis signals dismal prognosis in pediatric osteosarcoma; leaves open optimal surveillance strategies.
BACKGROUND: Secondary cardiac tumors are far more frequent than primary tumors. Cardiac metastasis of osteosarcoma is extremely rare. CASE PRESENTATION: We report a 14-year-old child with left femur osteosarcoma that had metastasized to the left ventricle after 30 months of follow-up. The diagnosis was confirmed based on the findings of transthoracic echocardiography and fluorodeoxyglucose positron emission tomography/computed tomography. Surgical removal was indicated in the patient, but his parents refused this decision, and the patient was discharged and admitted to a pediatric oncology center for chemotherapy. The patient died after four courses of chemotherapy. CONCLUSION: Cardiac metastasis of osteosarcoma is a strong predictor of disease. The demographic differences shown in our case include male sex and a short interval between onset and cardiac involvement.
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Snoussi et al. (2020) conducted a case report in Left ventricular metastasis of osteosarcoma (n=1). Chemotherapy was evaluated on Survival. A 14-year-old male with left femur osteosarcoma developed rare left ventricular metastasis after 30 months and died following four courses of chemotherapy.
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