Key result
Multimodality imaging guides successful resection of metastatic osteosarcoma involving the tricuspid subvalvular apparatus.
Why the study?
Cardiac metastases from osteosarcoma are exceedingly rare and often diagnosed late, representing a major diagnostic challenge.
Case Report (n=1)
No
This case emphasizes the necessity of multimodality imaging for differentiating complex intracardiac masses and underscores that cardiac metastasis should be considered in patients with advanced malignancy presenting with cardiovascular symptoms.
May facilitate resection in rare symptomatic cases; leaves open routine multimodality imaging in osteosarcoma.
BACKGROUND: Cardiac metastases from osteosarcoma are exceedingly rare and often diagnosed late, representing a major diagnostic challenge. CASE SUMMARY: A 17-year-old boy with a history of osteosarcoma presented with dyspnea and palpitations. Transthoracic echocardiography revealed a mobile intracardiac mass attached to the tricuspid subvalvular apparatus with partial right ventricular outflow tract obstruction. Cardiac magnetic resonance demonstrated a lesion with heterogeneous signal intensity and late gadolinium enhancement, suggestive of malignancy. Surgical resection was performed, and histopathology confirmed metastatic osteosarcoma. DISCUSSION: This case highlights the importance of multimodality imaging in the evaluation of intracardiac masses and underscores the need to consider cardiac metastasis in patients with advanced malignancy and atypical cardiac symptoms.
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Melem et al. (2026) conducted a case report in Cardiac metastasis from osteosarcoma (n=1). Multimodality imaging and surgical resection was evaluated on Diagnosis and surgical resection of intracardiac mass. Multimodality imaging accurately identified a metastatic osteosarcoma involving the tricuspid subvalvular apparatus, allowing for successful surgical resection and complete resolution of symptoms.
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