Key result
Peritoneal dialysis linked to ~91% fewer ADHF hospitalization days in refractory heart failure.
Why the study?
Previous small studies suggested benefits of peritoneal dialysis in chronic refractory heart failure, but larger cohort data excluding end-stage renal disease were lacking.
Does peritoneal dialysis reduce hospitalization days in patients with chronic refractory heart failure?
Population
126 patients with chronic refractory heart failure excluding end-stage renal disease in two French medical centers
Comparison
Peritoneal dialysis therapy versus baseline clinical parameters before PD initiation
Design
Retrospective cohort study
Follow-up
1 year
Authors
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PD was associated with fewer ADHF hospitalizations in refractory HF; hypothesis-generating and should not yet change practice.
Cohort (n=126)
Yes
Does peritoneal dialysis reduce hospitalization days in patients with chronic refractory heart failure?
Absolute Event Rate: 0.3% vs 3.3%
p-value: p=<0.0001
In patients with chronic refractory heart failure, peritoneal dialysis significantly reduces hospitalization days for acute decompensated heart failure and improves left ventricular ejection fraction.
Courivaud et al. (2013) conducted a cohort in chronic refractory heart failure (n=126). Peritoneal dialysis vs. Pre-initiation baseline was evaluated on number of days of hospitalization for acute decompensated heart failure (days/patient-month) (p=<0.0001). Peritoneal dialysis significantly reduced hospitalization days for acute decompensated heart failure from 3.3 to 0.3 days/patient-month (p<0.0001) in patients with refractory heart failure.
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