Key result
Remimazolam induction linked to unexpected delayed anesthesia emergence, promptly reversed by flumazenil.
Why the study?
Despite remimazolam's ultrashort-acting properties and minimal impact on respiratory and cardiovascular functions, delayed emergence after a single intravenous induction dose has been observed.
Population
63-year-old patient with atrial fibrillation and reduced ejection fraction undergoing laparoscopic cholecystectomy
Comparison
Remimazolam induction with sufentanil and rocuronium versus usual emergence expectations
Design
Case report
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May cause delayed emergence after single-bolus remimazolam; hypothesis-generating for incidence and risk factors.
Case Report (n=1)
Remimazolam can cause delayed emergence from anesthesia even after a single bolus dose, which can be successfully reversed with flumazenil.
A 2023 study conducted a case report in Gallbladder stones (n=1). Remimazolam was evaluated on Delayed emergence from anesthesia. A single intravenous induction dose of remimazolam (0.3 mg/kg) resulted in unexpected delayed emergence from anesthesia in a 63-year-old patient, which was promptly reversed by flumazenil.
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