What question did this study set out to answer?

This research aims to report severe cardiovascular collapses associated with remimazolam during anesthesia induction in elderly patients.

July 7, 2026CureusOpen Access

Severe Cardiovascular Collapse Associated With Remimazolam-Based Anesthetic Induction: A Case Series of Three Elderly Patients

View Full Paper

Ask AI

Bookmark

Authors

Case series reports severe cardiovascular collapse in elderly patients induced with remimazolam, suggesting hypersensitivity reactions.

This research aims to report severe cardiovascular collapses associated with remimazolam during anesthesia induction in elderly patients.
Case series of three elderly patients experiencing cardiovascular collapse during anesthetic induction with remimazolam.
Review of six suspected hypersensitivity reactions over 18 months among elderly patients after anesthesia induction.
Clinical features included cardiovascular or respiratory instability, end-tidal CO₂ reduction, and hypotension.
Three patients experienced severe cardiovascular collapse requiring epinephrine and CPR.
Two patients progressed to cardiac arrest with minimal cutaneous manifestations.
Evidence of mast-cell activation through elevated histamine or tryptase levels was noted in selected cases.

Kim et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

July 7, 2026CureusOpen Access

View Full Paper

Ask AI

Bookmark

Authors

Case series reports severe cardiovascular collapse in elderly patients induced with remimazolam, suggesting hypersensitivity reactions.

This research aims to report severe cardiovascular collapses associated with remimazolam during anesthesia induction in elderly patients.
Case series of three elderly patients experiencing cardiovascular collapse during anesthetic induction with remimazolam.
Review of six suspected hypersensitivity reactions over 18 months among elderly patients after anesthesia induction.
Clinical features included cardiovascular or respiratory instability, end-tidal CO₂ reduction, and hypotension.
Three patients experienced severe cardiovascular collapse requiring epinephrine and CPR.
Two patients progressed to cardiac arrest with minimal cutaneous manifestations.
Evidence of mast-cell activation through elevated histamine or tryptase levels was noted in selected cases.

Kim et al. (2026) studied this question.

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark