Key result
Eight weeks of aerobic exercise reduces serum visfatin ~13% and improves lipids in sedentary men.
Why the study?
The effects of aerobic exercise training on visfatin, homocystein, C-reactive protein, and lipid profile in sedentary men were not well established.
Does aerobic exercise training improve visfatin, homocysteine, C-reactive protein, and lipid profile in sedentary men?
Does aerobic exercise training improve visfatin, homocysteine, C-reactive protein, and lipid profile in sedentary men?
Absolute Event Rate: 90.92% vs 104.54%
p-value: p=0.005
Eight weeks of aerobic exercise improves lipid profiles and reduces visfatin levels in sedentary men, suggesting a benefit for cardiovascular risk reduction.
May confer metabolic benefits in sedentary men; hypothesis-generating for cardiovascular risk reduction and needs randomized confirmation.
Background and objectives: Visfatin is a newly characterized adipokine, which is highly expressed in visceral adipose tissue.The aim of this study was to evaluate effects of aerobic exercise training on visfatin, homocystein, C-reactive protein and lipid profile in sedentary men. Methods:In this quasi-experimental study, 27 sedentary men were selected by convenience sampling method.The subjects were divided into a control group (n=13) and an aerobic training group (n=14).The subjects in the experimental group performed 60 minutes of aerobic exercise at 75-85% of maximum heart rate, three sessions per week for eight weeks.Data were analyzed in SPSS 16.0 (SPSS Inc., Chicago, IL, USA) using paired and independent sample t-test for comparison of means within and between groups, respectively.A P-value of less than 0.05 was considered statistically significant.Results: The eight-week aerobic exercise training significantly reduced body weight (P=0.02),body mass index (P=0.01)and low-density lipoprotein-cholesterol (P=0.03)levels.It also caused a significant increase in the high-density-lipoprotein-cholesterol (P=0.00) and a significant decrease in visfatin levels (P=0.005).Serum homocysteine and Creactive protein levels decreased by the end of the training program, but these changes were not statistically significant (P>0.05). Conclusion:The eight-week aerobic exercise program could effectively improve lipid profile and visfatin levels.Therefore, this type of exercise could be recommended for prevention of cardiovascular disease and improvement of its risk factors.
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Alavizadeh et al. (2018) studied Sedentary (n=27). Aerobic exercise vs. No exercise was evaluated on Serum visfatin levels (mg/ml) (p=0.005). Eight weeks of aerobic exercise significantly reduced serum visfatin levels (P=0.005) and improved lipid profiles in healthy sedentary men compared to a non-exercising control group.
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