Key result
Opioid use disorder is linked to ~44% higher 30-day readmission after cardiac surgery.
Why the study?
The impact of opioid use disorder on readmissions following cardiac operations was understudied despite known associations with increased morbidity and resource use.
Does opioid use disorder increase readmissions and complications in patients undergoing cardiac surgery?
Population
1,978,276 patients undergoing coronary artery bypass grafting and valve repair or replacement in the Nationwide Readmissions Database
Comparison
Patients with opioid use disorder vs patients without opioid use disorder
Design
Retrospective cohort study using Nationwide Readmissions Database
Follow-up
30 days
Authors
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May warrant enhanced discharge planning for cardiac surgery patients with opioid use disorder; leaves open whether interventions reduce readmissions.
Cohort (n=1,978,276)
Yes
Does opioid use disorder increase readmissions and complications in patients undergoing cardiac surgery?
Absolute Event Rate: 19% vs 13.2%
p-value: p=<0.001
Opioid use disorder in cardiac surgery patients is associated with higher rates of 30-day readmission, thromboembolic events, and infectious complications, highlighting the need for targeted predischarge interventions.
Madrigal et al. (2020) conducted a cohort in Patients undergoing cardiac operations (n=1,978,276). Opioid use disorder vs. Patients without opioid use disorder was evaluated on 30-day readmission (p=<0.001). Opioid use disorder in patients undergoing cardiac surgery was associated with a higher rate of 30-day readmission (19.0% vs 13.2%, p<0.001) compared to those without the disorder.
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