Key result
Atrial plus arterial switch is linked to similar survival but ~74% fewer reoperations than intraventricular rerouting.
Why the study?
The long-term follow-up prognosis after the double-switch operation for congenitally corrected transposition of the great arteries was uncertain.
Does an atrial switch plus arterial switch improve long-term outcomes compared to an atrial switch plus intraventricular rerouting in patients with congenitally corrected transposition of the great arteries?
Cohort (n=90)
No
Does an atrial switch plus arterial switch improve long-term outcomes compared to an atrial switch plus intraventricular rerouting in patients with congenitally corrected transposition of the great arteries?
Absolute Event Rate: 83.3% vs 75.7%
The double-switch operation for congenitally corrected transposition of the great arteries has acceptable long-term outcomes, with the atrial switch plus arterial switch approach showing lower morbidity regarding reoperation and arrhythmias.
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Supports preferring atrial-arterial switch in ccTGA to reduce reoperations; leaves open randomized confirmation of long-term outcomes.
Hiramatsu et al. (2012) conducted a cohort in Congenitally corrected transposition of the great arteries (n=90). Atrial switch plus arterial switch vs. Atrial switch plus intraventricular rerouting was evaluated on Kaplan-Meier survival at 20 years. Atrial switch plus arterial switch yielded similar 20-year survival (83.3% vs 75.7%) but higher freedom from reoperation (94.1% vs 77.6%, P<0.05) compared to intraventricular rerouting.
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