Why the study?
Does arterial switch operation improve long-term morbidity and quality of life compared to atrial switch operation in patients with transposition of the great arteries?
Population
302 patients who underwent surgical repair of transposition of the great arteries at a single institution…
Comparison
Arterial switch operation (n=80) vs Atrial switch operation (n=222)
Design
Cohort
Follow-up
mean 14.5±10.1 years
Key result
Arterial switch operation was associated with higher early mortality but comparable long-term survival and quality of life, and fewer arrhythmias compared to atrial switch repair.
Authors
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Arterial switch may reduce arrhythmias in TGA; leaves open optimal repair strategy given higher early mortality in observational data.
Cohort (n=302)
No
Does arterial switch operation improve long-term morbidity and quality of life compared to atrial switch operation in patients with transposition of the great arteries?
While arterial switch operation for TGA has higher early mortality than atrial switch, it offers comparable long-term survival and quality of life with a lower incidence of postoperative arrhythmias.
Gorler et al. (2011) conducted a cohort in Transposition of the great arteries (TGA) (n=302). Arterial switch operation vs. Atrial switch operation was evaluated on Long-term morbidity, survival, and quality of life. Arterial switch operation was associated with higher early mortality but comparable long-term survival and quality of life, and fewer arrhythmias compared to atrial switch repair.
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