Key result
Early splenectomy alone extends symptom-free survival to ~9 years in a primary splenic angiosarcoma case.
Why the study?
Primary angiosarcoma of the spleen is a very rare and aggressive sarcoma with typically poor outcomes and limited data on long-term survival.
Highlights a rare case of long-term symptom-free survival (9 years) following splenectomy for primary splenic angiosarcoma, a disease typically associated with a 1-2 year mean survival.
Answers are grounded in this paper and cite their sources.
Early splenectomy may extend survival in primary splenic angiosarcoma; this Level 5 case leaves open the need for prospective confirmation.
Primary angiosarcoma of the spleen is a very rare but very aggressive soft tissue sarcoma due to early dissemination. The outcome of this disease is typically dismal with a mean survival of one to two years. However, our here presented case remained uncommonly symptom-free for nine years after splenectomy alone at the early phase of the disease.
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Liu et al. (2012) studied this question. Splenectomy alone during the early phase of primary splenic angiosarcoma led to a nine-year symptom-free survival, contrasting with the typical mean survival of one to two years.
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