Key result
Anticoagulation clears apical thrombus after 3 months in an SLE patient with persistent Takotsubo ballooning.
Why the study?
Takotsubo cardiomyopathy is typically transient with favorable prognosis, but cases of persistent apical ballooning and complications like apical thrombus are not well characterized.
Case Report (n=1)
No
Highlights that Takotsubo cardiomyopathy may not always be transient and can be complicated by left ventricular thrombus.
Answers are grounded in this paper and cite their sources.
Supports consideration of extended anticoagulation for thrombus in persistent Takotsubo; leaves open generalizability beyond this SLE case.
Takotsubo cardiomyopathy, which is also known as "transient apical ballooning", is a cardiac syndrome associated with emotional and physical stress that occurs in postmenopausal women. It may mimic acute coronary syndrome but coronary angiography reveals normal epicardial coronary arteries. The prognosis is favorable with the normalization of wall motion abnormalities within weeks. We report a case of persistent apical ballooning complicated by an apical thrombus in Takotsubo cardiomyopathy of systemic lupus erythematous patient. Takotsubo cardiomyopathy may not be always transient and left ventricular thrombus can occur in the disease course as our patient.
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Shim et al. (2013) conducted a case report in Takotsubo cardiomyopathy and Systemic Lupus Erythematosus (n=1). Anticoagulation therapy (heparin and warfarin) was evaluated on Resolution of apical thrombus and apical ballooning. In a 63-year-old woman with systemic lupus erythematosus, Takotsubo cardiomyopathy presented with persistent apical ballooning and an apical thrombus that resolved after 3 months of anticoagulation therapy.
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