Key result
Overweight and obesity linked to a ~0.5-day shorter LOS in non-ICU COVID-19 patients.
Why the study?
The mechanism for the possible association between obesity and poor clinical outcomes from COVID-19 remains unclear.
Does BMI category affect length of stay in adult COVID-19 patients?
Cohort (n=22,915)
Yes
Does BMI category affect length of stay in adult COVID-19 patients?
There is an unexpected dose-dependent, inverse relationship between BMI category and length of stay for COVID-19 patients admitted to non-intensive care.
Answers are grounded in this paper and cite their sources.
Should not yet alter non-ICU COVID-19 care; leaves open confounding by indication in Level 5 data.
Background: The mechanism for possible association between obesity and poor clinical outcomes from Coronavirus Disease 2019 (COVID-19) remains unclear. Methods: We analyzed 22,915 adult COVID-19 patients hospitalized from March 2020 to April 2021 to non-intensive care using the American Heart Association National COVID Registry. A multivariable Poisson model adjusted for age, sex, medical history, admission respiratory status, hospitalization characteristics, and laboratory findings was used to calculate length of stay (LOS) as a function of body mass index (BMI). We similarly analyzed 5,327 patients admitted to intensive care for comparison. Results: <0.01, respectively). Conclusion: The model identified a dose-dependent, inverse relationship between BMI category and LOS for COVID-19, which was not seen when the model was applied to critically ill patients.
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Collins et al. (2022) conducted a cohort in COVID-19 (n=22,915). Overweight and Obesity vs. Normal BMI (18.5 to < 25 kg/m2) was evaluated on Length of stay (LOS) (MD -0.469 days, 95% CI -0.708 to -0.231, p=<0.01). Relative to normal BMI, overweight, class I obese, and class II obese patients hospitalized for COVID-19 in non-intensive care had approximately half-day reductions in length of stay.
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