Key result
Diastolic dysfunction affects ~44% of asymptomatic T2DM patients, linked to age and poor glycemic control.
Why the study?
Diastolic dysfunction in type 2 diabetes mellitus patients without cardiac manifestations was not well characterized to recognize early cardiac involvement.
What is the prevalence of diastolic dysfunction in patients with type 2 diabetes mellitus without cardiac manifestations?
Cross-Sectional (n=54)
No
What is the prevalence of diastolic dysfunction in patients with type 2 diabetes mellitus without cardiac manifestations?
Diastolic dysfunction is highly prevalent (44.4%) in asymptomatic type 2 diabetes patients, correlating with disease duration and poor glycemic control.
Background: Diabetes is the commonest metabolic disorder affecting the people all over the world. Objective of the study was to identify the diastolic dysfunction in type 2 diabetes mellitus patient to recognize the early involvement of heart.Methods: This cross sectional study was conducted in tertiary care hospital cases of type II diabetes mellitus coming to our hospital and giving informed consent. Period of study was from September 2016 to February 2018. Consecutive type of non-probability sampling was used for the selection of study subjects. A total of 54 diagnosed patients of type II diabetes mellitus coming to our hospital and giving informed consent were included in the study.Results: Prevalence of diastolic dysfunction was observed to be 44.4% in patients of type 2 diabetes mellitus without cardiac manifestations. Prevalence of diastolic dysfunction was seen in 47.4% males in comparison to 42.9% females. Prevalence of diastolic dysfunction was 11.1%, 77.3% and 80% in cases with disease duration of 0-5 years, 6-10 years and more than 10 years respectively. Prevalence of diastolic dysfunction was more in cases with poor glycaemic control i.e. hemoglobin A1c (HbA1c) value >8% as compared to cases with good glycemic control.Conclusions: There was an association between the prevalence of diastolic dysfunction with the increasing age. We had higher percentage of patients with diastolic dysfunction as duration of diabetes increased. Diastolic dysfunction was seen in 55.2% patients receiving oral hypoglycaemic agents (OHAs) as compared to 23.5% patients who were on insulin and 50% patients who were on both insulin and OHAs.
No takes yet. Share an insight, caveat, or question.
Khade et al. (2020) conducted a cross-sectional in Type 2 diabetes mellitus without cardiac manifestations (n=54). Type 2 diabetes mellitus was evaluated on Prevalence of diastolic dysfunction. Diastolic dysfunction was present in 44.4% of patients with type 2 diabetes mellitus without cardiac manifestations, with higher prevalence associated with increasing age, longer disease duration, and poor glycemic control.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: