Key result
Oral disopyramide restores sinus rhythm in ~54% of supraventricular arrhythmia patients with minimal hemodynamic complications.
Why the study?
Does oral disopyramide safely induce reversion to sinus rhythm in patients with supraventricular cardiac arrhythmias?
Population
35 patients with supraventricular cardiac arrhythmias
Design
Case series of oral disopyramide treatment
Authors
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Hypothesis-generating for oral disopyramide in supraventricular arrhythmias; prospective randomized trials needed before clinical adoption.
Does oral disopyramide safely induce reversion to sinus rhythm in patients with supraventricular cardiac arrhythmias?
Oral disopyramide appears to be an effective and safe antiarrhythmic drug for reverting supraventricular cardiac arrhythmias to sinus rhythm.
Sloman et al. (1977) studied this question. Oral disopyramide restored sinus rhythm in 19 of 35 patients with supraventricular arrhythmias, with 18 of those 19 experiencing no major hemodynamic complications.
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