E. A. COCKAYNE, D.M., F.R.C.P; CLEFT PALATE, HARE LIP, DACRYOCYSTITIS, AND CLEFT HAND AND FEET, Biometrika, Volume 28, Issue 1-2, 1 June 1936, Pages 60–63, http
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E. A. Cockayne (1936) studied this question.