Investigation of haemodynamic changes in schisto- somal cor pulmonale showed:(A) The presence of broncho-pulmonary arterial shunts proved by: (1) absence of correlation between the size of the pulmonary artery and its luminal pressure; (2) a progressive increase in the oxygen saturation in the pulmonary artery along its course;(3) the appearance in the pulmonary artery in 12 seconds of Evans blue dye injected into the aorta; (4) a sudden increase in the pressure as the catheter was drawn from the wedge to the pre-wedge position; and (5) on aorto- graphy by a special technique, the rapid filling of the big branches of the pulmonary artery through the bronchial arteries.(B) The presence of splenic shunts, as evidenced by: (1) a fall in the oxygen saturation in the inferior vena cava after splenectomy; and (2) a change towards normal in the size of the heart, in the electrocardiogram, and in the pulmonary arterial pressure after splenectomy.
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Afkar Badawy (1962) studied this question.