Key result
Supervised CR is linked to a ~29% VO2peak improvement in high-risk patients, matching lower-risk peers.
Why the study?
The effect and safety of cardiac rehabilitation exercise training in high-risk cardiac patients compared to controls without high-risk criteria were unclear.
Does a 6 to 8 week supervised cardiac rehabilitation exercise training program safely improve VO2peak and LVEF in high-risk cardiac patients compared to non-high-risk controls?
Cohort (n=24)
No
Does a 6 to 8 week supervised cardiac rehabilitation exercise training program safely improve VO2peak and LVEF in high-risk cardiac patients compared to non-high-risk controls?
Supervised cardiac rehabilitation is safe and effective for improving exercise capacity and ejection fraction even in high-risk cardiac patients with advanced heart failure or recent arrhythmias.
May support supervised cardiac rehabilitation in high-risk patients; extends observational data but remains hypothesis-generating pending RCTs.
Objective To examine the effect and safety of cardiac rehabilitation (CR) program in high-risk cardiac patients and compare these results to those of control CR participants without high-risk criteria.Methods A total of 12 high-risk cardiac patients were recruited as subjects.The high-risk criteria were: advanced heart failure with left ventricular ejection fraction (LVEF) of less than 30%, a recent history of cardiac arrest or dangerous arrhythmia, and cardiac device insertion.Another 12 CR participants without any high-risk criteria mentioned above were recruited as controls.Both groups underwent 6 to 8 weeks of CR exercise training.Exercise tolerance tests were performed before and after completion of the CR program.After CR completion, both groups were evaluated and their results were compared.Results After completion of the CR exercise program, both groups showed significant increases in peak oxygen uptake (VO 2peak ) and LVEF.In the control group (n=12), VO 2peak increased from 25.9 to 31.8 mL/kg/min (changing rate, +21.4%±22.1%)and LVEF increased from 56.1% to 59.1% (changing rate, +5.3%±8.4%).In the high-risk group (n=12), VO 2peak increased from 16.8 to 21.0 mL/kg/min (changing rate, +28.6%±21.4%)and LVEF increased from 26.1% to 29.4% (changing rate, +16.1%±12.9%).There was no serious cardiovascular event during all exercise hours.Conclusion High-risk cardiac patients who completed a supervised CR program demonstrated significant improvements in VO 2peak and LVEF without any serious cardiovascular event.The improvement rate was similar to that of control group.
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Choi et al. (2017) conducted a cohort in High-risk cardiac disease (n=24). Supervised cardiac rehabilitation exercise training vs. Non-high-risk cardiac patients undergoing the same cardiac rehabilitation program was evaluated on Change rate in peak oxygen uptake (VO2peak) (p=0.551). A 6- to 8-week supervised cardiac rehabilitation program significantly improved peak oxygen uptake by 28.6% in high-risk cardiac patients, an improvement rate similar to that of non-high-risk patients (21.5%).
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