Association and predictive value of the triglyceride glucose-weight adjusted waist index for cardiovascular outcomes in patients with type 2 diabetes

Figures

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  Fig. 1. Study participant selection of this study.

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  Fig. 2. Kaplan–Meier curves for cardiovascular outcomes and total mortality based on baseline TyG-WWI quartiles. (A) MACEs; (B) CVD mortality; (C) Nonfatal MI; (D) Nonfatal stroke; (E) Major-CHD; (F) CHF; (G) Total mortality. MACEs major adverse cardiovascular events; CVD cardiovascular disease; MI myocardial infarction; CHD coronary heart disease events; CHF congestive heart failure; TyG-WWI triglyceride glucose-weight adjusted waist index.

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  Fig. 3. Restricted cubic spline analysis and smooth curve fitting analysis were used to evaluate the relationship between TyG-WWI and primary and secondary outcomes. A, Restricted cubic spline analysis; B, Smooth curve fitting analysis. The hazard ratios shown are adjusted for Model 3, including sex, race, age, height, education, living alone, and smoking, history of cardiovascular disease, previous hypertension, previous hyperlipidemia, proteinuria, heart failure, depression, duration of diabetes, SBP, DBP, HbA1c, TC, LDL-C, HDL-C, eGFR, diuretics, CCBs, beta-blockers, biguanides, meglitinides, thiazolidinediones, insulins, statins, fibrates, cholesterol absorption inhibitors, and aspirins.

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  Fig. 4. Subgroup analysis and interaction analysis were performed to examine the relationship between TyG-WWI and outcome events. (A) MACEs; (B) Major-CHD; (C) CHF; (D) total mortality. TyG-WWI, triglyceride glucose-weight adjusted waist index; MACEs major adverse cardiovascular events; CHD coronary heart disease events; CHF congestive heart failure.

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  Fig. 5. ROC analysis of cardiovascular outcomes and total mortality. (A) MACEs; (B) Major-CHD; (C) CHF; (D) total mortality. TyG-WWI, triglyceride glucose-weight adjusted waist index; MACEs major adverse cardiovascular events; CHD coronary heart disease events; CHF congestive heart failure.