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March 10, 2025RadioprotectionOpen Access

Diagnostic reference levels based on clinical indications for paediatric computed tomography examinations at the Mohammed VI University Hospital Center in Marrakech-Morocco

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Key result

Paediatric CT DRLs vary by clinical indication, falling below European and African standards for head trauma.

  • P<0.01
  • n=1,730

Why the study?

Diagnostic reference levels based on clinical indications for paediatric CT examinations were not established at the Mohammed VI University Hospital Centre in Marrakech.

Population

1730 paediatric CT examinations across three age groups (1–5, 5–10, 10–15 years)

Comparison

Diagnostic reference levels based on clinical indications vs published international standards from Europe and Africa

Design

Retrospective observational study at a single centre

Discussion

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Member takes

Overview

Provides institution-specific pediatric CT DRLs by indication and age; leaves open validation and dose-optimization impact beyond this center.

Study Design

Type

Observational (n=1,730)

Multicenter

No

Structured PICO

P
Population
1,730 paediatric CT examinations across three age groups (1-15 years) analyzed to derive diagnostic reference levels based on clinical indications.
E
Exposure
Derivation of diagnostic reference levels based on clinical indications (DRL CI)
C
Comparator
Published international standards from Europe and Africa
O
Outcome
Diagnostic reference levels (median and third quartile values of dose index CTDI vol and dose-length product DLP distributions) for 14 distinct clinical indicationssurrogate

Main Result

p-value: p=<0.01

The study establishes clinical indication-based diagnostic reference levels for pediatric CTs in a Moroccan hospital, finding them generally higher than European but lower than African standards.

Cite This Study

A 2025 study conducted an observational in Paediatric computed tomography (n=1,730). Computed tomography (CT) examinations was evaluated on Diagnostic reference levels (CTDI vol and DLP) based on clinical indications (p=<0.01). Diagnostic reference levels for paediatric CT varied significantly between clinical indications for CTDI vol (p<0.01), with head trauma DRLs lower than European and African standards.

synapsesocial.com/papers/6aae1a3612edec67d4879d7dhttps://doi.org/10.1051/radiopro/2025008
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnostic reference levels determined based on clinical indications for adult computed tomography at the Mohammed VI University Hospital Centre in Marrakech, Morocco.2026
  2. 2Comment on “Diagnostic reference levels based on clinical indications for paediatric computed tomography examinations at the Mohammed VI University Hospital Center in Marrakech-Morocco”2026
  3. 3Diagnostic reference levels for adult Computed Tomography at the University Hospital Center of Marrakech (MOROCCO).2024 · 2 citations
  4. 4Local diagnostic reference levels for paediatric computed tomography based on European guidelines: anatomy- and indication-based approaches2026
  5. 5Proposed typical diagnostic reference levels in paediatric radiography exams2026