Key result
Colorectal surgery at age ≥85 linked to higher mortality and pulmonary complications despite similar five-year survival.
Why the study?
Risk factors for mortality, morbidity, and long-term survival in very old patients with colorectal cancer compared with old patients were evaluated to inform surgical decisions.
Does surgery for colorectal cancer in patients ≥85 years old have acceptable mortality and survival compared to patients 75-84 years old?
Comparison
Patients aged 75-84 years vs patients aged 85 years or older
Design
Cohort study
Follow-up
Up to 5 years
Authors
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Higher perioperative risks in ≥85-year-olds; leaves open whether age alone should guide colorectal cancer surgery decisions.
Cohort (n=114)
Does surgery for colorectal cancer in patients ≥85 years old have acceptable mortality and survival compared to patients 75-84 years old?
p-value: p=0.0477
Very old patients (≥85 years) with colorectal cancer have higher perioperative risks but similar long-term survival compared to those aged 75-84, suggesting age alone should not preclude surgery.
Takeuchi et al. (2004) conducted a cohort in Colorectal cancer (n=114). Age >=85 years vs. Age 75-84 years was evaluated on Mortality rate (p=0.0477). Patients aged ≥85 years operated on for colorectal cancer had significantly higher mortality (P=0.0477) and pulmonary complications (P=0.0019) than those aged 75-84, but similar 5-year survival.
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