Key result
Pediatric GFR equations outperform adult formulas in young adults by avoiding substantial GFR overestimation.
Why the study?
The performance of creatinine-based equations to estimate GFR in adolescents and young adults is poorly understood.
Do pediatric GFR estimating equations improve the accuracy of GFR estimation compared to adult equations in adolescents and young adults?
Cross-Sectional (n=751)
Do pediatric GFR estimating equations improve the accuracy of GFR estimation compared to adult equations in adolescents and young adults?
Pediatric GFR estimating equations provide more accurate estimates of GFR than adult equations in adolescents and young adults up to age 26.
No takes yet. Share an insight, caveat, or question.
May favor pediatric over adult GFR equations in adolescents and young adults; cross-sectional data leaves open need for prospective validation.
Selistre et al. (2012) reported a cross-sectional. Creatinine-based GFR estimating equations vs. Inulin clearance (measured GFR) was evaluated on Agreement between estimating formulas and measured GFR. Pediatric GFR estimating equations showed good correlation with measured GFR in adolescents and young adults, whereas adult formulas substantially overestimated measured GFR.
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