Getting a look in: A high-throughput screening method has been developed for the identification and isolation of enantioselective hydrolases displayed on cell surfaces (see scheme; E: Esterase, P: Peroxidase). Enantiomeric substrates labeled with two different fluorescent dyes allow real-time analysis of enantioselectivity by determination of the ratio of green and red single-cell fluorescence.
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Becker et al. (2008) studied this question.
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