Key result
Microalbuminuria affects ~37% of Indian patients with T2D, linked to higher HbA1c and disease duration.
Why the study?
Microalbuminuria is an early indicator of kidney damage in uncontrolled diabetes linked with elevated cardiovascular and renal risks, but its prevalence and clinical predictors in Indian T2DM patients were not well defined.
What is the prevalence and what are the clinical predictors of microalbuminuria in Indian patients with type 2 diabetes?
Observational (n=63,570)
Yes
What is the prevalence and what are the clinical predictors of microalbuminuria in Indian patients with type 2 diabetes?
Odds Ratio: 1.18
p-value: p=<0.001
Nearly 40% of Indian patients with type 2 diabetes have microalbuminuria, emphasizing the importance of routine screening to detect early kidney damage and mitigate cardiovascular risk.
Emphasizes screening consideration in Indian T2D; extends observational predictor data but leaves optimal strategies open pending prospective trials.
Context: Microalbuminuria (MAU) is an early indicator of kidney damage in uncontrolled diabetes linked with elevated cardiovascular and renal risks. Aims: This study aims to determine the prevalence of MAU and identify clinical predictors in type 2 diabetes mellitus (T2DM) patients. Settings and Design: A retrospective, multicenter analysis of clinical records from 2600 diabetes centers across India, conducted during the “World Diabetes Day” campaign (November 14–30, 2022). Materials and Methods: Clinical records of 63,570 T2DM patients screened using Micral ® test for MAU were analyzed. Data on demographics, comorbidities, and clinical parameters were collected. Statistical Analysis Used: The statistical analyses were conducted using R Studio Version 2022.07.2. Results: MAU prevalence was 36.9% ( n = 17,275). The mean age of patients was 54.8 ± 11.9 years, with 64% being male. Key predictors included hemoglobin A1c (odds ratio [OR] = 1.18, P < 0.001), diabetes duration (OR = 1.04, P < 0.001), hypertension duration (OR = 1.03, P < 0.001), and diastolic BP (OR = 1.01, P < 0.001). Males had slightly lower odds of MAU compared to females (OR = 0.96, P = 0.198). Conclusions: Four out of ten patients with type 2 diabetes suffered from MAU in our study. Therefore, it is strongly recommended to screen every diabetes patient in clinical practice to detect early signs of kidney damage.
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Sahay et al. (2025) conducted an observational in Type 2 diabetes mellitus (n=63,570). Elevated Hemoglobin A1c was evaluated on Microalbuminuria (MAU) (OR 1.18, p=<0.001). In Indian patients with type 2 diabetes, the prevalence of microalbuminuria was 36.9%, with hemoglobin A1c (OR 1.18, P<0.001) and diabetes duration (OR 1.04, P<0.001) identified as key predictors.
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